Sunday, September 2, 2018

Withdrawing from a sleeping pill in practice


At your risk.
This is not a medical advice.
It can be dangerous.
Psychological, psychiatric supervision, family support is very important.


2 persons decided to withdraw gradually, decreasing a well known Benzodiazepine pill. They were taking it for years. It was increased at times. Current dose is 2.5mg per day.


A half time (time for dose to become half) of 6 months was decided. The dose will be 1/2 is 6 months. 1/2 of 1/2 in another 6 months ie 1/4 in a year. 1/8 in a year and 6 months. 1/16 in 2 years etc.


So the number to multiply for every day dose from the previous day dose is 0.9954. This is a negative interest rate. Or an exponential reduction. See also how the curve of the voltage across a discharging capacitor looks like. See how this number is derived from a previous post. Roughly the pill of any next day is 1% less than the pill of any previous day.


By weighting a whole pill with a digital micro weighing balance a mass of 0.200g was found. Ie 200μg.


So the dose for first day is 200μg.


For next day the dose is 200x0.9954 ie 199.08μg. In practice 199μg. The mass of the pill is reduced by using a small file.


For the day after the dose is 199.08 x 0.9954 = 198.16μg
Note how the rate of reduction drops


The day after the day after the dose is 197.25μg


There is a fluctuation error or 2μg from the balance used. So it is somewhat like dither noise reduction. The doses are not exact. Would this actually help the brain in withdrawal?



















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